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This medication may cause severe adverse effects, including severe dermatologic reactions, serious and potentially fatal conditions such as Toxic epidermal necrolysis, DRESS syndrome (Drug Reaction (or Rash) with Eosinophilia and Systemic Symptoms), and Stevens-Johnson Syndrome. The symptoms of these diseases may include fever, sore throat, headache, and vomiting with a severe blistering, peeling, and red skin rash. Modafinil may also have a contraceptive effect which lasts for a month after cessation of dosage. Always consult with a specialist before taking any medication.

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